Otitis externa (OE) is an infection of the external auditory canal affecting children and adults and is associated with symptoms of local pain and tenderness. Twice-daily topical treatment with ofloxacin otic solution (0.3% ) for 10 days has been reported to be as effective and well tolerated as neomycin sulfate-polymyxin B sulfate-hydrocortisone otic suspension (Cortisporin otic suspension) administered four times daily for 10 days.
The various forms of ophthalmic pharmaceutical presentation of steroids is proliferating on the market: solutions, gels, and suspensions. Suspensions are characterized by particles in solution and require agitation before instillation. This trial studied the impact of agitation on the corticoid concentration of eye drop solutions, gels, and suspensions.
Dexamethasone Solution-Suspension – Ophthalmic-Otic
This medication is used to treat certain eye conditions due to inflammation or injury. Dexamethasone works by relieving symptoms such as swelling, redness, and itching. It belongs to a class of drugs known as corticosteroids.
Difference Between Suspension and Solution
Chemistry is the physical science which deals with matter and the changes that it goes through during chemical reactions. It deals with the chemical reaction between substances that are mixed together and how they are transformed into another substance.
Cortisporin Otic Suspension
CORTISPORIN Otic Solution (neomycin and polymyxin B sulfates and hydrocortisone otic solution, USP) is a sterile antibacterial and anti-inflammatory solution for otic use. Each mL contains: neomycin sulfate equivalent to 3.5 mg neomycin base, polymyxin B sulfate equivalent to 10,000 polymyxin B units, and hydrocortisone 10 mg (1%). The vehicle contains potassium metabisulfite 0.1% (added as a preservative) and the inactive ingredients cupric sulfate, glycerin, hydrochloric acid, propylene glycol, and Water for Injection.
Most Recent Comparisons
Vision and hearing are the two most crucial aspects of human life. Try to imagine a dark world without any sound. Pretty dull, right? All the surrounding information that our mind gathers, most of it passes through two portals; our eyes and our ears. So, when it comes to treating these two senses, utmost care is required. You can’t pour in anything in your eyes and ears which are available in the market. Remember, trying to self-diagnose your eye and ear infection can potentially harm your eyesight and your hearing.
Topical Fluoroquinolones for Eye and Ear
Since fluoroquinolone antibiotics were introduced for systemic use in the 1980s, their indications and use have increased rapidly. Recently, topical formulations for the eye and ear have appeared, expanding the options for the treatment of certain bacterial infections.
Cortisporin Otic Solution Sterile
Combinations of Corticosteroids with Antibacterials
Ophthalmological Corticosteroid and Anti-infective Combinations
Otic Corticosteroid-anti-infective Combinations
Topical Aminoglycosides, Plain or in Combination
Topical Polypeptide Anti-infectives, Plain or in Combination