Comprehensive Characterization of Dispersions using STEP-Technology
L.U.M. GmbH, market leader in innovative instruments to analyse stability, shelf life, particle size distribution of semi-diluted or concentrated dispersions, presents a new technological platform for comprehensive dispersion analysis, realized in the product lines LUMiSizer®, LUMiFuge® and LUMiReader®.
A centrifuge is a device that separates particles from a solution through use of a rotor. In biology, the particles are usually cells, subcellular organelles, or large molecules, all of which are referred to here as particles.
VI. Common Centrifugation Vocabulary and Formulas.
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Centrifugal separation of a mixture
"Fluid Dynamics Research" whose first volume was published in 1986 is the official journal of the JSFM. "Fluid Dynamics Research" is a well-established international journal of Fluid Mechanics, published six times per year by IOPP (Institute of Physics Publishing) on behalf of the JSFM since 2009.
Centrifuge Rotor Types: Swinging Bucket vs. Fixed Angle
Regardless of your application and rotor design, centrifugation is a powerful tool for separation of micro- and macro-molecules in solutions. Centrifuges of all types and sizes are used every day for biological analysis in forensic investigations (such as separating and studying blood and urine), pharmaceutical development (characterizing macromolecules), food purity (like removing fat from milk), and wastewater management (separating “sludge” and heavy metals from water).
Stability of Diazoxide in Extemporaneously Compounded Oral Suspensions
The objective of this study was first to develop and validate a stability-indicating HPLC-UV method for diazoxide and then to evaluate the stability of simple preparations of this drug compounded in Oral Mix and Oral Mix Sugar Free (SF). The suspensions were prepared from the bulk diazoxide powder as well as from diazoxide capsules. Oral Mix and Oral Mix SF are frequently used, dye-free, cherry flavoured oral suspending vehicles from Medisca Pharmaceutique Inc.
The above equation indicates that the rate of sedimentation can be reduced by minimizing the density difference between the suspended particles and the liquid phase, reducing the particle size, and increasing the viscosity of the liquid phase.
Results: The QF drug contents in OB and OS for 90 days were not significantly different compared to day 0 at two temperatures. QF in OB remained dissolved over time at two temperatures, whereas QF in OS was precipitated out at day 7 and 90. The pH of both OB and OS preparations was consistent from day 0 to day 90. There were no significant differences in visual appearance or odor for both OB and OS preparations overtime at two temperatures.